Insulin Reduces Inflammation by Regulating the Activation of the NLRP3 Inflammasome

The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is the platform for IL-1β maturation, aimed at mediating a rapid immune response against danger signals which must be tightly regulated. Insulin is well known as the critical hormone in the maintenance of glucose in physiolog...

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Bibliographic Details
Main Authors: Yu-Wei Chang, Ling-Chien Hung, Yu-Cheng Chen, Wen-Hung Wang, Chun-Yu Lin, Hsin-Han Tzeng, Jau-Ling Suen, Yen-Hsu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
ASC
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.587229/full