Lipid Drug Carriers for Cancer Therapeutics: An Insight into Lymphatic Targeting, P-gp, CYP3A4 Modulation and Bioavailability Enhancement

Lipid Drug Carriers for Cancer Therapeutics: An Insight into Lymphatic Targeting, P-gp, CYP3A4 Modulation and Bioavailability Enhancement

In the treatment of cancer, chemotherapy plays an important role though the efficacy of anti-cancer drug administered orally is limited, due to their poor solubility in physiological medium, inability to cross biological membrane, high Para-glycoprotein (P-gp) mediated drug efflux, and pre-systemic...

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Bibliographic Details
Main Authors: Shashank Chaturvedi, Anurag Verma, Vikas Anand Saharan
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2020-08-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
lipid based carriers
lymphatic system
metastasis
p-gp
cyp3a4
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-10-524.pdf

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