Cancer-associated fibroblast-derived exosomal microRNA-98-5p promotes cisplatin resistance in ovarian cancer by targeting CDKN1A

Cancer-associated fibroblast-derived exosomal microRNA-98-5p promotes cisplatin resistance in ovarian cancer by targeting CDKN1A

Abstract Background Ovarian cancer (OC) is a gynecological malignancy with a high mortality. Cisplatin-based treatment is the typical treatment regimen for OC patients; however, it may cause unfavorable resistance. The current study intends to explore the function of cancer-associated fibroblast (CA...

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Bibliographic Details
Main Authors: Hua Guo, Chunfang Ha, Hui Dong, Zhijuan Yang, Yuan Ma, Yonghui Ding
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cancer Cell International
Subjects:
Cancer-associated fibroblasts
Exosomes
microRNA-98-5p
CDKN1A
Ovarian cancer
Cisplatin resistance
Online Access:https://doi.org/10.1186/s12935-019-1051-3

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