Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways

Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways

Abstract Background Corticosteroids increase the expression of β2-adrenoceptors (β2-ARs) and protect them against down-regulation. Conversely, β2-AR agonists improve the anti-inflammatory action of corticosteroids. Nevertheless, it is still uncertain whether adding a long-acting β2-AR agonist (LABA)...

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Bibliographic Details
Main Authors: Luigino Calzetta, Maria Gabriella Matera, Francesco Facciolo, Mario Cazzola, Paola Rogliani
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Respiratory Research
Subjects:
ICS/LABA FDC
Asthma
Interaction
Medium bronchi
Small airways
Online Access:http://link.springer.com/article/10.1186/s12931-018-0770-7

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