Insights From Analysis of Human Antigen-Specific Memory B Cell Repertoires

Insights From Analysis of Human Antigen-Specific Memory B Cell Repertoires

Memory B cells that are generated during an infection or following vaccination act as sentinels to guard against future infections. Upon repeat antigen exposure memory B cells differentiate into new antibody-secreting plasma cells to provide rapid and sustained protection. Some pathogens evade or su...

Full description

Bibliographic Details
Main Authors: Hemangi B. Shah, Kenneth Smith, Jonathan D. Wren, Carol F. Webb, Jimmy D. Ballard, Rebecka L. Bourn, Judith A. James, Mark L. Lang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
memory B cells
vaccination
monoclonal antibody
antibody repertoires
next generation sequencing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03064/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03064/full

Similar Items