Effects of Naltrexone on Large-Scale Network Interactions in Methamphetamine Use Disorder

Effects of Naltrexone on Large-Scale Network Interactions in Methamphetamine Use Disorder

Naltrexone attenuates craving, and the subjective effects of methamphetamine and extended-release naltrexone (XR-NTX) reduces functional connectivity between regions of the striatum and limbic cortex. Naltrexone modulates neural activity at dopaminergic synapses; however, it is unclear whether naltr...

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Bibliographic Details
Main Authors: Milky Kohno, Angelica M. Morales, Laura E. Dennis, Holly McCready, William F. Hoffman, P. Todd Korthuis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Psychiatry
Subjects:
naltrexone
resting-state functional magnetic resonance imaging
methamphetamine
striatum
functional connectivity
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00603/full

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