Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase

Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase

The obligatory first step in the removal of cholesterol from foam cells is the hydrolysis of stored cholesteryl esters (CEs) to release free cholesterol (FC). Neutral cholesteryl ester hydrolase (CEH) catalyzes this hydrolysis, and limiting levels of CEH could play a role in determining the suscepti...

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Bibliographic Details
Main Authors:	Shobha Ghosh, Richard W. St. Clair, Lawrence L. Rudel
Format:	Article
Language:	English
Published:	Elsevier 2003-10-01
Series:	Journal of Lipid Research
Subjects:	reverse cholesterol transport cholesterol efflux atherosclerosis macrophage foam cells cholesteryl ester
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520337007

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