The identification of zebrafish mutants showing alterations in senescence-associated biomarkers.
There is an interesting overlap of function in a wide range of organisms between genes that modulate the stress responses and those that regulate aging phenotypes and, in some cases, lifespan. We have therefore screened mutagenized zebrafish embryos for the altered expression of a stress biomarker,...
Main Authors: | Shuji Kishi, Peter E Bayliss, Junzo Uchiyama, Eriko Koshimizu, Jie Qi, Purushothama Nanjappa, Shintaro Imamura, Asiful Islam, Donna Neuberg, Adam Amsterdam, Thomas M Roberts |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-08-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2515337?pdf=render |
Similar Items
-
Embryonic senescence and laminopathies in a progeroid zebrafish model.
by: Eriko Koshimizu, et al.
Published: (2011-01-01) -
Embryonic Senescence and Laminopathies in a Progeroid Zebrafish Model
by: Koshimizu, Eriko, et al.
Published: (2011) -
A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis.
by: Shintaro Imamura, et al.
Published: (2008-01-01) -
alms1 mutant zebrafish do not show hair cell phenotypes seen in other cilia mutants.
by: Lauren Parkinson, et al.
Published: (2021-01-01) -
Zebrafish Hagoromo mutants upregulate fgf8 post-embryonically and develop neuroblastoma
by: Amsterdam, Adam, et al.
Published: (2012)