Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprung’s disease

Four new loci associations discovered by pathway-based and network analyses of the genome-wide variability profile of Hirschsprung’s disease

<p>Abstract</p> <p>Finding gene associations in rare diseases is frequently hampered by the reduced numbers of patients accessible. Conventional gene-based association tests rely on the availability of large cohorts, which constitutes a serious limitation for its application in thi...

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Bibliographic Details
Main Authors: Fernández Raquel Ma, Bleda Marta, Núñez-Torres Rocío, Medina Ignacio, Luzón-Toro Berta, García-Alonso Luz, Torroglosa Ana, Marbà Martina, Enguix-Riego Ma Valle, Montaner David, Antiñolo Guillermo, Dopazo Joaquín, Borrego Salud
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Orphanet Journal of Rare Diseases
Subjects:
HSCR
Pathway-based analysis
Network analysis
GWAS
Online Access:http://www.ojrd.com/content/7/1/103

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