Evaluation of Dexamethasone as an Antiemetic in Laparoscopic Cholecystectomy

• Main Author: Jawad Zaheer
• Format: Article
• Language: English
• Published: Rawalpindi Medical University 2010-12-01
• Series: Journal of Rawalpindi Medical College
• Subjects: Laparoscopic cholecystectomy; nausea and vomiting; Dexamethasone.
• Online Access: https://www.journalrmc.com/index.php/JRMC/article/view/660

Background: To determine whether intravenous Dexamethasone (8mg), during anaesthesia, would decrease early postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy (LC). Methods: In this double- blind, randomized controlled trial, hundred patients who underwent laparoscopic cholecystectomy were divided in two groups. In Group-A, 50 patients, who received Inj. Dexamethasone 8 mg were compared with Group B, a control group of fifty patients who had laparoscopic cholecystectomy but did not receive Inj. Dexamethasone. Results: Group A showed low frequency of PONV when compared to Group B(nausea 6 vs. 27 and vomiting 3 vs. 13 , with p value of < 0.001 and < 0.006 respectively. Conclusion: Inj.Dexamethasone given during anaesthesia effectively controls postoperative nausea and vomiting.