Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy
<p>Abstract</p> <p>Background</p> <p>Human adenovirus serotype 5 (Ad5) has been widely explored as a gene delivery vector for a variety of diseases. Many target cells, however, express low levels of Ad5 native receptor, the Coxsackie-Adenovirus Receptor (CAR), and thus...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-10-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/4/1/103 |