Supercritical Fluid Extract of Spent Coffee Grounds Attenuates Melanogenesis through Downregulation of the PKA, PI3K/Akt, and MAPK Signaling Pathways

The mode of action of spent coffee grounds supercritical fluid CO2 extract (SFE) in melanogenesis has never been reported. In the study, the spent coffee grounds were extracted by the supercritical fluid CO2 extraction method; the chemical constituents of the SFE were investigated by gas chromatogra...

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Bibliographic Details
Main Authors: Huey-Chun Huang, Chien-Mei Wei, Jen-Hung Siao, Tsang-Chi Tsai, Wang-Ping Ko, Kuei-Jen Chang, Choon-Hoon Hii, Tsong-Min Chang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2016/5860296