Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities

Determination of Intrinsic Drug Dissolution and Solute Effective Transport Rate during Laminar Fluid Flow at Different Velocities

The objective of this study was to determine the intrinsic drug dissolution rate (IDR) and the solute effective transport rate of some drugs, using a single particle dissolution technique, satisfying qualified dissolution conditions. The IDR of three poorly water-soluble compounds was measured in mi...

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Bibliographic Details
Main Authors: Sara B. E. Andersson, Göran Frenning, Göran Alderborn
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
computational fluid dynamics
dissolution
fluid flow
intrinsic dissolution rate
microscopy
single particle dissolution
Online Access:https://www.mdpi.com/1999-4923/13/6/835

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