Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites

Background. Vascular cell adhesion molecule-1 (VCAM-1) is associated with ovarian cancer progression but the origin of its soluble form (sVCAM-1) in serum is not well investigated. The purpose of this study was to elucidate whether the concentration of sVCAM-1 in serum correlates with the concentrat...

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Bibliographic Details
Main Authors: Jakimovska Marina, Cerne Katarina, Verdenik Ivan, Kobal Borut
Format: Article
Language:English
Published: Sciendo 2014-09-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2013-0066
Description
Summary:Background. Vascular cell adhesion molecule-1 (VCAM-1) is associated with ovarian cancer progression but the origin of its soluble form (sVCAM-1) in serum is not well investigated. The purpose of this study was to elucidate whether the concentration of sVCAM-1 in serum correlates with the concentration in ascites, that represents local tumour environment, and with systemic inflammation, various clinicopathological characteristics, and patient outcome.
ISSN:1581-3207