Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape

The COPII coat assembles in two concentric layers and mediates protein export from the endoplasmic reticulum. Here the authors present the 4.9 Å resolution cryo-tomography and subtomogram averaging structure of the membrane bound COPII inner coat that was obtained by in vitro reconstitution and disc...

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Bibliographic Details
Main Authors: Joshua Hutchings, Viktoriya Stancheva, Elizabeth A. Miller, Giulia Zanetti
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06577-4