A preclinical perspective on the enhanced vulnerability to Alzheimer's disease after early-life stress

Stress experienced early in life (ES), in the form of childhood maltreatment, maternal neglect or trauma, enhances the risk for cognitive decline in later life. Several epidemiological studies have now shown that environmental and adult life style factors influence AD incidence or age-of-onset and e...

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Bibliographic Details
Main Authors: Lianne Hoeijmakers, Sylvie L. Lesuis, Harm Krugers, Paul J. Lucassen, Aniko Korosi
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Neurobiology of Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289517300486