Ubiquitin-mediated regulation of autophagy

Abstract Autophagy is a major degradation pathway that utilizes lysosome hydrolases to degrade cellular constituents and is often induced under cellular stress conditions to restore cell homeostasis. Another prime degradation pathway in the cells is ubiquitin-proteasome system (UPS), in which protei...

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Bibliographic Details
Main Authors: Ruey-Hwa Chen, Yu-Hsuan Chen, Tzu-Yu Huang
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Biomedical Science
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12929-019-0569-y