Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B Streptococcus Colonization and Infection

Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B Streptococcus Colonization and Infection

Group B Streptococcus (GBS) is a leading cause of neonatal morbidity and mortality, and the primary source of exposure is the maternal vagina. Intrapartum antibiotic prophylaxis for GBS-positive mothers has reduced the incidence of GBS early-onset disease, however, potential long-lasting influence o...

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Bibliographic Details
Main Authors: Gregory R. Lum, Vicki Mercado, Diede van Ens, Victor Nizet, Jacqueline M. Kimmey, Kathryn A. Patras
Format: Article
Language:English
Published: Karger Publishers 2021-05-01
Series:Journal of Innate Immunity
Subjects:
group b streptococcus
hypoxia-inducible factor 1 alpha
vaginal colonization
innate immunity
macrophage
Online Access:https://www.karger.com/Article/FullText/515739

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