| Summary: | Aim: In this study, we sought to evaluate the complications of Hereditary Multiple Exostosis (HME) particularly the presence of pain, and its effects on pediatric and adolescent groups.Patients and Methods: 72 (37male/32female) patients aging between 10-19 years were included in study. The mean age was 13.8±2.6 years. The demographic data of the patients, age at diagnosis, number of lesions, deformity and pain with VAS score were evaluated. The quality of life was evaluated with the use of a question-naire. Child Depression Scale (CDS) for the patients who were 17 years or younger and Hamilton Depression Scale (HAM-D) for the patients who were 18 or older, were used to evaluate the mood. The frequency and percentage of the group variables were noted, "t-test" was used to determine the differences between the two groups; one-way analysis of variance was used to compare more than two averages.Results: In our study 68.1% (n=49) of the patients had one or more surgical interven-tions due to HME. The most common complaint was pain in 72.2% (n=52) of patients. The most common cause that initiated pain was running 52.8% and contact sports (football, basketball, etc.) was reported in 50% of patients. 31.9% of the patients reported that the pain limited their daily activities, the mean VAS score was 7.4 ±2.4. Decreased VAS scores were significantly related with increased CDS scores. (p=0.005) Higher CDS and HAM-D scores were significantly related with the number of operations (p=0.015), the number of days with pain per month (p <0.001), lower VAS scores (p=0.005) and the number of lesions in the extremities (p=0.003)..Conclusion: Pain is a crucial problem that can limit sociocultural activities and inter-action in pediatric HME patients. The number of previous operations,number of days with pain per month and increased number of lesions are factors that negatively affect the quality of life and cause depression in HME patients.
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