An integrative genomic analysis of transcriptional profiles identifies characteristic genes and patterns in HIV-infected long-term non-progressors and elite controllers

An integrative genomic analysis of transcriptional profiles identifies characteristic genes and patterns in HIV-infected long-term non-progressors and elite controllers

Abstract Background Despite that most HIV-infected individuals experience progressive CD4+ T cell loss and develop AIDS, a minority of HIV-infected individuals remain asymptomatic and maintain high level CD4+ T cell counts several years after seroconversion. Efforts have been made to understand the...

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Bibliographic Details
Main Authors: Jiwei Ding, Ling Ma, Jianyuan Zhao, Yongli Xie, Jinming Zhou, Xiaoyu Li, Shan Cen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Journal of Translational Medicine
Subjects:
Elite controller
Long-term nonprogressor
Viremic nonprogressor
Meta-analysis
GSEA
WGCNA
Online Access:http://link.springer.com/article/10.1186/s12967-019-1777-7

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