Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

<p>Abstract</p> <p>Background</p> <p>The 70 kDa ribosomal protein S6 kinase (<it>RPS6KB1</it>), located at 17q23, is amplified and overexpressed in 10–30% of primary breast cancers and breast cancer cell lines. p70S6K is a serine/threonine kinase regulated b...

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Bibliographic Details
Main Authors: Hautaniemi Sampsa, Klefström Juha, Kallioniemi Anne, Saarela Matti, Nieminen Anni, Heinonen Henna, Monni Outi
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/348

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http://www.biomedcentral.com/1471-2164/9/348

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