Epidemiology of Brugada syndrome in Japan and rest of the world
Brugada syndrome is an inherited disease that causes sudden death because of ventricular fibrillation. Its prevalence is approximately 0.15% in adults and 0.005% in children in Asia, and less than 0.02% in the West. The reason for the higher prevalence in Asia is likely ethnic-specific polymorphisms...
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Wiley
2013-04-01
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| Series: | Journal of Arrhythmia |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1880427613000094 |
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doaj-d7cbc57b9e8044a48211446a7748f09e2020-11-24T21:12:33ZengWileyJournal of Arrhythmia1880-42762013-04-01292525510.1016/j.joa.2013.01.004Epidemiology of Brugada syndrome in Japan and rest of the worldShiro KamakuraBrugada syndrome is an inherited disease that causes sudden death because of ventricular fibrillation. Its prevalence is approximately 0.15% in adults and 0.005% in children in Asia, and less than 0.02% in the West. The reason for the higher prevalence in Asia is likely ethnic-specific polymorphisms modulating the activity of the primary disease-causing mutation. In Japan, the incidence of Brugada-pattern electrocardiogram (ECG) is 14.2 per 100,000 person-years. Data from multicenter registries indicate that its frequency in men with Brugada syndrome is higher in Japanese patients (94–96%) than in Caucasian patients (72–80%). Healthy individuals with Brugada-type ECG have a favorable prognosis with an annual death rate of less than 0.5%.http://www.sciencedirect.com/science/article/pii/S1880427613000094Brugada syndromePrevalenceIncidenceGender |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Shiro Kamakura |
| spellingShingle |
Shiro Kamakura Epidemiology of Brugada syndrome in Japan and rest of the world Journal of Arrhythmia Brugada syndrome Prevalence Incidence Gender |
| author_facet |
Shiro Kamakura |
| author_sort |
Shiro Kamakura |
| title |
Epidemiology of Brugada syndrome in Japan and rest of the world |
| title_short |
Epidemiology of Brugada syndrome in Japan and rest of the world |
| title_full |
Epidemiology of Brugada syndrome in Japan and rest of the world |
| title_fullStr |
Epidemiology of Brugada syndrome in Japan and rest of the world |
| title_full_unstemmed |
Epidemiology of Brugada syndrome in Japan and rest of the world |
| title_sort |
epidemiology of brugada syndrome in japan and rest of the world |
| publisher |
Wiley |
| series |
Journal of Arrhythmia |
| issn |
1880-4276 |
| publishDate |
2013-04-01 |
| description |
Brugada syndrome is an inherited disease that causes sudden death because of ventricular fibrillation. Its prevalence is approximately 0.15% in adults and 0.005% in children in Asia, and less than 0.02% in the West. The reason for the higher prevalence in Asia is likely ethnic-specific polymorphisms modulating the activity of the primary disease-causing mutation. In Japan, the incidence of Brugada-pattern electrocardiogram (ECG) is 14.2 per 100,000 person-years. Data from multicenter registries indicate that its frequency in men with Brugada syndrome is higher in Japanese patients (94–96%) than in Caucasian patients (72–80%). Healthy individuals with Brugada-type ECG have a favorable prognosis with an annual death rate of less than 0.5%. |
| topic |
Brugada syndrome Prevalence Incidence Gender |
| url |
http://www.sciencedirect.com/science/article/pii/S1880427613000094 |
| work_keys_str_mv |
AT shirokamakura epidemiologyofbrugadasyndromeinjapanandrestoftheworld |
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1716750694647595008 |