Optogenetic recruitment of dorsal raphe serotonergic neurons acutely decreases mechanosensory responsivity in behaving mice.

Optogenetic recruitment of dorsal raphe serotonergic neurons acutely decreases mechanosensory responsivity in behaving mice.

The inhibition of sensory responsivity is considered a core serotonin function, yet this hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic approach to induce acute, robust and specific firing of dorsal raphe serotonergic neurons. In vitro, the responsiveness...

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Bibliographic Details
Main Authors: Guillaume P Dugué, Magor L Lörincz, Eran Lottem, Enrica Audero, Sara Matias, Patricia A Correia, Clément Léna, Zachary F Mainen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4141837?pdf=render

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http://europepmc.org/articles/PMC4141837?pdf=render

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