Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling

Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling

Propolis has abundant polyphenolic constituents and is used widely as a health/functional food. Here, we investigated the effects of polyphenol-rich propolis extracts (PPE) on intestinal barrier function in human intestinal epithelial Caco-2 cells, as well as in rats. In Caco-2 cells, PPE increased...

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Bibliographic Details
Main Authors: Kai Wang, Xiaolu Jin, Yifan Chen, Zehe Song, Xiasen Jiang, Fuliang Hu, Michael A. Conlon, David L. Topping
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Nutrients
Subjects:
propolis
tight junctions
Caco-2
AMPK
ERK
Online Access:http://www.mdpi.com/2072-6643/8/5/272

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