The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages.

The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages.

Oxidative stress is key in the pathogenesis of several diseases including age-related macular degeneration (AMD), atherosclerosis, diabetes, and Alzheimer's disease. It has previously been established that a lipid peroxidation product, carboxyethylpyrrole (CEP), accumulates in the retinas of AM...

Full description

Bibliographic Details
Main Authors: Ali M Saeed, Stephanie Duffort, Dmitry Ivanov, Hua Wang, James M Laird, Robert G Salomon, Fernando Cruz-Guilloty, Victor L Perez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4153630?pdf=render

Internet

http://europepmc.org/articles/PMC4153630?pdf=render

Similar Items