Nicotine promotes acquisition of stem cell and epithelial-to-mesenchymal properties in head and neck squamous cell carcinoma.

The ability of nicotine to enhance the malignancy of cancer cells is known; however, the possibility that nicotine could regulate a cancer stem cell phenotype remains to be well-established. In this study we sought to determine whether long-term exposure to nicotine could promote cancer stem cell-li...

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Bibliographic Details
Main Authors: Michael Andrew Yu, Alan Kiang, Jessica Wang-Rodriguez, Elham Rahimy, Martin Haas, Vicky Yu, Lesley G Ellies, Jing Chen, Jian-Bing Fan, Kevin T Brumund, Robert A Weisman, Weg M Ongkeko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530520?pdf=render