Diverged Effects of Piperine on Testicular Development: Stimulating Leydig Cell Development but Inhibiting Spermatogenesis in Rats

Background: Piperine is the primary pungent alkaloid isolated from the fruit of black peppercorns. Piperine is used frequently in dietary supplements and traditional medicines. The objective of the present study was to investigate the effects of piperine on the testis development in the pubertal rat...

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Bibliographic Details
Main Authors: Xianwu Chen, Fei Ge, Jianpeng Liu, Suhao Bao, Yong Chen, Dongli Li, Yong Li, Tongliang Huang, Xiaofang Chen, Qiqi Zhu, Qingquan Lian, Ren-Shan Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Pharmacology
Subjects:
rat
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00244/full