Tubular overexpression of gremlin induces renal damage susceptibility in mice.

A growing number of patients are recognized worldwide to have chronic kidney disease. Glomerular and interstitial fibrosis are hallmarks of renal progression. However, fibrosis of the kidney remains an unresolved challenge, and its molecular mechanisms are still not fully understood. Gremlin is an e...

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Bibliographic Details
Main Authors: Alejandra Droguett, Paola Krall, M Eugenia Burgos, Graciela Valderrama, Daniel Carpio, Leopoldo Ardiles, Raquel Rodriguez-Diez, Bredford Kerr, Katherina Walz, Marta Ruiz-Ortega, Jesus Egido, Sergio Mezzano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4103765?pdf=render