Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling
Optogenetic tools have been used to control cellular behaviours but their use to probe structure-function relations of signalling proteins are underexplored. Here the authors engineer optogenetic modules into STIM1 to dissect molecular details of STIM1-mediated signalling and control various cellula...
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Bibliographic Details
Main Authors: |
Guolin Ma,
Lian He,
Shuzhong Liu,
Jiansheng Xie,
Zixian Huang,
Ji Jing,
Yi-Tsang Lee,
Rui Wang,
Hesheng Luo,
Weidong Han,
Yun Huang,
Yubin Zhou |
Format: | Article
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Language: | English |
Published: |
Nature Publishing Group
2020-02-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-020-14841-9
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