Modification of insulin amyloid aggregation by Zr phthalocyanines functionalized with dehydroacetic acid derivatives.

Amyloid fibrils are widely studied both as target in conformational disorders and as basis for the development of protein-based functional materials. The three Zr phthalocyanines bearing dehydroacetic acid residue (PcZr(L1)2) and its condensed derivatives (PcZr(L2)2 and PcZr(L3)2) as out-of-plane li...

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Main Authors: Svitlana Chernii, Yuriy Gerasymchuk, Mykhaylo Losytskyy, Damian Szymański, Iryna Tretyakova, Anna Łukowiak, Vasyl Pekhnyo, Sergiy Yarmoluk, Viktor Chernii, Vladyslava Kovalska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243904