MDM2 amplification and fusion gene ss18-ssx in a poorly differentiated synovial sarcoma: A rare but puzzling conjunction

MDM2 amplification and fusion gene ss18-ssx in a poorly differentiated synovial sarcoma: A rare but puzzling conjunction

The detection of specific alterations by genetic analyses has been included in the diagnostic criterions of the World Health Organization’s classification of soft tissues tumors since 2013. The presence of a SS18 rearrangement is pathognomonic of synovial sarcoma (SS). MDM2 amplification is strongly...

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Bibliographic Details
Main Authors: Ilaria Di Mauro, Lénaïg Mescam-Mancini, Bruno Chetaille, Marick Lae, Gaelle Pierron, Bérengère Dadone-Montaudie, Audrey Bazin, Corinne Bouvier, Jean-François Michiels, Florence Pedeutour
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Synovial sarcoma
Amplification
Diagnosis
Liposarcoma
MDM2
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301202

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http://www.sciencedirect.com/science/article/pii/S1476558620301202

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