Immunity Against Leishmania major Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection

Immunity Against Leishmania major Infection: Parasite-Specific Granzyme B Induction as a Correlate of Protection

Zoonotic cutaneous leishmaniasis (ZCL) caused by Leishmania (L.) major infection is characterized by different clinical presentations which depend in part on the host factors. In attempt to investigate the impact of the host's immune response in the outcome of the disease, we conducted a prospe...

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Bibliographic Details
Main Authors: Thouraya Boussoffara, Sadok Chelif, Melika Ben Ahmed, Mourad Mokni, Afif Ben Salah, Koussay Dellagi, Hechmi Louzir
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Leishmania major
specific-cytotoxicity
granzyme B
correlate of protection
re-infection
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00397/full

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