Identification and in vitro Characterization of a Novel Phage Endolysin that Targets Gram-Negative Bacteria

Most double-stranded (ds) DNA phages utilize holin proteins to secrete endolysin for host peptidoglycan lysis. In contrast, several holin-independent endolysins with secretion sequences or signal-arrest-release (SAR) sequences are secreted via the Sec pathway. In this study, we characterized a novel...

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Bibliographic Details
Main Authors: Jaewoo Bai, Sangmi Lee, Sangryeol Ryu
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/8/3/447