Total saponins in Rubus parvifolius L. induce lymphoma cells apoptosis through upregulated Bax/Fas and downregulated Bcl-2 in vivo and in vitro

Total saponins in Rubus parvifolius L. induce lymphoma cells apoptosis through upregulated Bax/Fas and downregulated Bcl-2 in vivo and in vitro

Purpose: To investigate the effect of total saponins of Rubus parvifolius L. (TSRP) on lymphoma Raji cells and further discuss its mechanism. Methods: The model of nude mice bearing Raji cells was established, the volume, weight and inhibition rate of the transplanted tumor were analyzed and compare...

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Bibliographic Details
Main Authors: Xu Xiao-Feng, Cheng Ru-Bin, Zhang Xue-Jin, Gao Rui-Lan
Format: Article
Language:English
Published: Hong Kong Gold Orchid Science and Technology Co., Limited 2019-03-01
Series:Traditional Medicine Research
Subjects:
Total Saponins of Rubus parvifolius L
Bcl-2
Bax
Fas
Apoptosis
Lymphoma
Online Access:https://www.tmrjournals.com/tmr/EN/10.12032/TMR20190304108

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