Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation

<p>Abstract</p> <p>Detailed study of glial inflammation has been hindered by lack of cell culture systems that spontaneously demonstrate the "neuroinflammatory phenotype". Mice expressing a glycine → alanine substitution in cytosolic Cu, Zn-superoxide dismutase (G93A-SOD1...

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Main Authors: Qi Min, Pye Quentin N, Potapova Tamara, Nguyen Kim, Mou Shenyun, Mhatre Molina, Hunter Jerrod, Abdel-Moaty Haitham, Hensley Kenneth, Rice Heather, Stewart Charles, Stroukoff Katharine, West Melinda
Format: Article
Language:English
Published: BMC 2006-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/3/1/2