Shedding new light on circadian clocks
Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains.
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2013-04-01
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doaj-d762a89dbfc2400fad4ca5686fb1042f2021-05-04T22:25:56ZengeLife Sciences Publications LtdeLife2050-084X2013-04-01210.7554/eLife.00659Shedding new light on circadian clocksMaud Demarque0Ueli Schibler1Department of Molecular Biology, University of Geneva, Geneva, Switzerlandthe Department of Molecular Biology, University of Geneva, Geneva, SwitzerlandUsing a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains.https://elifesciences.org/articles/00659Clock geneUSF1genetic modifiercircadian rhythmmouse geneticChIP-Seq |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Maud Demarque Ueli Schibler |
spellingShingle |
Maud Demarque Ueli Schibler Shedding new light on circadian clocks eLife Clock gene USF1 genetic modifier circadian rhythm mouse genetic ChIP-Seq |
author_facet |
Maud Demarque Ueli Schibler |
author_sort |
Maud Demarque |
title |
Shedding new light on circadian clocks |
title_short |
Shedding new light on circadian clocks |
title_full |
Shedding new light on circadian clocks |
title_fullStr |
Shedding new light on circadian clocks |
title_full_unstemmed |
Shedding new light on circadian clocks |
title_sort |
shedding new light on circadian clocks |
publisher |
eLife Sciences Publications Ltd |
series |
eLife |
issn |
2050-084X |
publishDate |
2013-04-01 |
description |
Using a clever combination of genetic and biochemical tools researchers have shown that a transcription factor called USF1 has a central role in determining how mutations of the Clock gene manifest themselves in the behaviour of different mouse strains. |
topic |
Clock gene USF1 genetic modifier circadian rhythm mouse genetic ChIP-Seq |
url |
https://elifesciences.org/articles/00659 |
work_keys_str_mv |
AT mauddemarque sheddingnewlightoncircadianclocks AT uelischibler sheddingnewlightoncircadianclocks |
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