Preparation and Characterization of Gelatin-Based Mucoadhesive Nanocomposites as Intravesical Gene Delivery Scaffolds

This study aimed to develop optimal gelatin-based mucoadhesive nanocomposites as scaffolds for intravesical gene delivery to the urothelium. Hydrogels were prepared by chemically crosslinking gelatin A or B with glutaraldehyde. Physicochemical and delivery properties including hydration ratio, visco...

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Bibliographic Details
Main Authors: Ching-Wen Liu, Li-Ching Chang, Kai-Jen Lin, Tsan-Jung Yu, Ching-Chung Tsai, Hao-Kuang Wang, Tong-Rong Tsai
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/473823