Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells.

Tubular epithelial cells (TECs) can be dedifferentiated by repetitive insults, which activate scar-producing cells generated from interstitial cells such as fibroblasts, leading to the accumulation and deposition of extracellular matrix molecules. The dedifferentiated TECs play a crucial role in the...

Full description

Bibliographic Details
Main Authors: Mitsugu Omata, Yukiko Doke, Chikaomi Yamada, Kayoko Kawashima, Rumiko Sho, Kei Enomoto, Mayumi Furuya, Norio Inomata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4873210?pdf=render