Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway

Since the incidence of breast cancer increases dramatically all over the world, the search for effective treatment is an urgent need. Metformin has demonstrated anti-tumorigenic effect both in vivo and in vitro in different cancer types. This work was designed to examine on molecular level the mode...

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Bibliographic Details
Main Authors: Nahla E El-Ashmawy, Naglaa F Khedr, Hoda A El-Bahrawy, Hend E Abo Mansour
Format: Article
Language:English
Published: IOS Press 2017-04-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317692235