The Role of c-erbB-2 Oncogene in Breast Carcinoma

Several factors have been identified in breast carcinoma which affect the biologic behavior, therapy and the prognosis of the tumor. Among these, c-erbB-2 (HER-2/neu) oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the Epidermal Growth Factor receptor. In this st...

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Main Authors: Seyda Erdogan, Melek Ergin, Ilhan Tuncer
Format: Article
Language:Turkish
Published: Cukurova University Faculty of Medicine 2003-06-01
Series:Arsiv Kaynak Tarama Dergisi
Subjects:
Online Access:http://www.scopemed.org/fulltextpdf.php?mno=19580
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spelling doaj-d753d486bb2e4c97b1056b5caba2874a2020-11-24T21:29:56ZturCukurova University Faculty of MedicineArsiv Kaynak Tarama Dergisi1300-37552003-06-01123157165The Role of c-erbB-2 Oncogene in Breast Carcinoma Seyda ErdoganMelek ErginIlhan TuncerSeveral factors have been identified in breast carcinoma which affect the biologic behavior, therapy and the prognosis of the tumor. Among these, c-erbB-2 (HER-2/neu) oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the Epidermal Growth Factor receptor. In this study, we discuss the prognostic role of c-erbB-2 oncoprotein overexpression in breast carcinoma with and without other parameters on the base of literature. [Archives Medical Review Journal 2003; 12(3.000): 157-165]http://www.scopemed.org/fulltextpdf.php?mno=19580c-erbB-2 OncogeneBreast Carcinoma
collection DOAJ
language Turkish
format Article
sources DOAJ
author Seyda Erdogan
Melek Ergin
Ilhan Tuncer
spellingShingle Seyda Erdogan
Melek Ergin
Ilhan Tuncer
The Role of c-erbB-2 Oncogene in Breast Carcinoma
Arsiv Kaynak Tarama Dergisi
c-erbB-2 Oncogene
Breast Carcinoma
author_facet Seyda Erdogan
Melek Ergin
Ilhan Tuncer
author_sort Seyda Erdogan
title The Role of c-erbB-2 Oncogene in Breast Carcinoma
title_short The Role of c-erbB-2 Oncogene in Breast Carcinoma
title_full The Role of c-erbB-2 Oncogene in Breast Carcinoma
title_fullStr The Role of c-erbB-2 Oncogene in Breast Carcinoma
title_full_unstemmed The Role of c-erbB-2 Oncogene in Breast Carcinoma
title_sort role of c-erbb-2 oncogene in breast carcinoma
publisher Cukurova University Faculty of Medicine
series Arsiv Kaynak Tarama Dergisi
issn 1300-3755
publishDate 2003-06-01
description Several factors have been identified in breast carcinoma which affect the biologic behavior, therapy and the prognosis of the tumor. Among these, c-erbB-2 (HER-2/neu) oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the Epidermal Growth Factor receptor. In this study, we discuss the prognostic role of c-erbB-2 oncoprotein overexpression in breast carcinoma with and without other parameters on the base of literature. [Archives Medical Review Journal 2003; 12(3.000): 157-165]
topic c-erbB-2 Oncogene
Breast Carcinoma
url http://www.scopemed.org/fulltextpdf.php?mno=19580
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