The Role of c-erbB-2 Oncogene in Breast Carcinoma
Several factors have been identified in breast carcinoma which affect the biologic behavior, therapy and the prognosis of the tumor. Among these, c-erbB-2 (HER-2/neu) oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the Epidermal Growth Factor receptor. In this st...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Turkish |
| Published: |
Cukurova University Faculty of Medicine
2003-06-01
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| Series: | Arsiv Kaynak Tarama Dergisi |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=19580 |
| Summary: | Several factors have been identified in breast carcinoma which affect the biologic behavior, therapy and the prognosis of the tumor. Among these, c-erbB-2 (HER-2/neu) oncogene encodes a transmembrane tyrosine kinase receptor with extensive homology to the Epidermal Growth Factor receptor. In this study, we discuss the prognostic role of c-erbB-2 oncoprotein overexpression in breast carcinoma with and without other parameters on the base of literature. [Archives Medical Review Journal 2003; 12(3.000): 157-165] |
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| ISSN: | 1300-3755 |