Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

Transcriptome analysis of microglia in a mouse model of Rett syndrome: differential expression of genes associated with microglia/macrophage activation and cellular stress

Abstract Background Rett syndrome (RTT) is a severe, neurodevelopmental disorder primarily affecting girls, characterized by progressive loss of cognitive, social, and motor skills after a relatively brief period of typical development. It is usually due to de novo loss of function mutations in the...

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Bibliographic Details
Main Authors: Dejian Zhao, Ryan Mokhtari, Erika Pedrosa, Rayna Birnbaum, Deyou Zheng, Herbert M. Lachman
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Molecular Autism
Subjects:
Microglia
Rett syndrome
Autism
Schizophrenia
Heat shock
M1 activation
Online Access:http://link.springer.com/article/10.1186/s13229-017-0134-z

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http://link.springer.com/article/10.1186/s13229-017-0134-z

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