Stochastic analysis of the SOS response in Escherichia coli.

BACKGROUND: DNA damage in Escherichia coli evokes a response mechanism called the SOS response. The genetic circuit of this mechanism includes the genes recA and lexA, which regulate each other via a mixed feedback loop involving transcriptional regulation and protein-protein interaction. Under norm...

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Bibliographic Details
Main Authors: Yishai Shimoni, Shoshy Altuvia, Hanah Margalit, Ofer Biham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2675100?pdf=render