Dimerization of Protegrin-1 in Different Environments

The dimerization of the cationic β-hairpin antimicrobial peptide protegrin-1 (PG1) is investigated in three different environments: water, the surface of a lipid bilayer membrane, and the core of the membrane. PG1 is known to kill bacteria by forming oligomeric membrane pores, which permeabilize the...

Full description

Bibliographic Details
Main Authors: Yiannis N. Kaznessis, Victor Vivcharuk
Format: Article
Language:English
Published: MDPI AG 2010-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/11/9/3177/