PD-1 Affects the Immunosuppressive Function of Group 2 Innate Lymphoid Cells in Human Non-Small Cell Lung Cancer

PD-1 Affects the Immunosuppressive Function of Group 2 Innate Lymphoid Cells in Human Non-Small Cell Lung Cancer

BackgroundThere is increasing evidence that group 2 innate lymphoid cells (ILC2s) play an essential role in allergy and parasitic infection. However, the role of ILC2s in human lung cancer remains unclear.MethodsILC2s from peripheral blood mononuclear cells (PBMCs) obtained from healthy donors (HDs)...

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Bibliographic Details
Main Authors: Chunyi Shen, Chaojun Liu, Zhen Zhang, Yu Ping, Jingwen Shao, Yonggui Tian, Weina Yu, Guohui Qin, Shasha Liu, Liping Wang, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
innate immune response
non-small cell lung cancer
programmed cell death protein 1
group 2 innate lymphoid cells
type 2 macrophage
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.680055/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.680055/full

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