Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group
Abstract. The objective of this guideline is to aid clinicians in making individual salvage treatment plans for pediatric and adolescent patients with first relapse or refractory (R/R) classical Hodgkin lymphoma (cHL). While salvage with standard dose chemotherapy followed by high dose chemotherapy...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2020-02-01
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| Series: | HemaSphere |
| Online Access: | http://journals.lww.com/10.1097/HS9.0000000000000329 |
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doaj-d7343141f1694de29a9be7c8815068712020-11-25T02:50:48ZengWolters KluwerHemaSphere2572-92412020-02-0141e32910.1097/HS9.0000000000000329202002000-00005Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma GroupStephen DawDirk HasencleverMaurizio MascarinAna Fernández-TeijeiroWalentyna BalwierzAuke BeishuizenRoberta BurnelliMichaela CepelovaAlexander ClaviezKarin DieckmannJudith Landman-ParkerRegine KlugeDieter KörholzChristine Mauz-KörholzWilliam Hamish WallaceThierry Leblancon behalf of the EuroNet Paediatric Hodgkin Lymphoma GroupAbstract. The objective of this guideline is to aid clinicians in making individual salvage treatment plans for pediatric and adolescent patients with first relapse or refractory (R/R) classical Hodgkin lymphoma (cHL). While salvage with standard dose chemotherapy followed by high dose chemotherapy and autologous stem cell transplant is often considered the standard of care in adult practice, pediatric practice adopts a more individualized risk stratified and response adapted approach to salvage treatment with greater use of non-transplant salvage. Here, we present on behalf of the EuroNet Pediatric Hodgkin Lymphoma group, evidence and consensus-based guidelines for standardized diagnostic, prognostic and response procedures to allocate children and adolescents with R/R cHL to stratified salvage treatments.http://journals.lww.com/10.1097/HS9.0000000000000329 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Stephen Daw Dirk Hasenclever Maurizio Mascarin Ana Fernández-Teijeiro Walentyna Balwierz Auke Beishuizen Roberta Burnelli Michaela Cepelova Alexander Claviez Karin Dieckmann Judith Landman-Parker Regine Kluge Dieter Körholz Christine Mauz-Körholz William Hamish Wallace Thierry Leblanc on behalf of the EuroNet Paediatric Hodgkin Lymphoma Group |
| spellingShingle |
Stephen Daw Dirk Hasenclever Maurizio Mascarin Ana Fernández-Teijeiro Walentyna Balwierz Auke Beishuizen Roberta Burnelli Michaela Cepelova Alexander Claviez Karin Dieckmann Judith Landman-Parker Regine Kluge Dieter Körholz Christine Mauz-Körholz William Hamish Wallace Thierry Leblanc on behalf of the EuroNet Paediatric Hodgkin Lymphoma Group Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group HemaSphere |
| author_facet |
Stephen Daw Dirk Hasenclever Maurizio Mascarin Ana Fernández-Teijeiro Walentyna Balwierz Auke Beishuizen Roberta Burnelli Michaela Cepelova Alexander Claviez Karin Dieckmann Judith Landman-Parker Regine Kluge Dieter Körholz Christine Mauz-Körholz William Hamish Wallace Thierry Leblanc on behalf of the EuroNet Paediatric Hodgkin Lymphoma Group |
| author_sort |
Stephen Daw |
| title |
Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group |
| title_short |
Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group |
| title_full |
Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group |
| title_fullStr |
Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group |
| title_full_unstemmed |
Risk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group |
| title_sort |
risk and response adapted treatment guidelines for managing first relapsed and refractory classical hodgkin lymphoma in children and young people. recommendations from the euronet pediatric hodgkin lymphoma group |
| publisher |
Wolters Kluwer |
| series |
HemaSphere |
| issn |
2572-9241 |
| publishDate |
2020-02-01 |
| description |
Abstract. The objective of this guideline is to aid clinicians in making individual salvage treatment plans for pediatric and adolescent patients with first relapse or refractory (R/R) classical Hodgkin lymphoma (cHL). While salvage with standard dose chemotherapy followed by high dose chemotherapy and autologous stem cell transplant is often considered the standard of care in adult practice, pediatric practice adopts a more individualized risk stratified and response adapted approach to salvage treatment with greater use of non-transplant salvage. Here, we present on behalf of the EuroNet Pediatric Hodgkin Lymphoma group, evidence and consensus-based guidelines for standardized diagnostic, prognostic and response procedures to allocate children and adolescents with R/R cHL to stratified salvage treatments. |
| url |
http://journals.lww.com/10.1097/HS9.0000000000000329 |
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