Target-selective joint polymerase chain reaction: A robust and rapid method for high-throughput production of recombinant monoclonal antibodies from single cells
<p>Abstract</p> <p>Background</p> <p>During the development of a therapeutic antibody, large numbers of monoclonal antibodies are required to screen for those that are best suited for the desired activity. Although the single cell-based immunoglobulin variable gene clon...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
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Series: | BMC Biotechnology |
Online Access: | http://www.biomedcentral.com/1472-6750/11/75 |