Exhausted cytotoxic control of Epstein-Barr virus in human lupus.

Exhausted cytotoxic control of Epstein-Barr virus in human lupus.

Systemic Lupus Erythematosus (SLE) pathology has long been associated with an increased Epstein-Barr Virus (EBV) seropositivity, viremia and cross-reactive serum antibodies specific for both virus and self. It has therefore been postulated that EBV triggers SLE immunopathology, although the mechanis...

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Main Authors: Martin Larsen, Delphine Sauce, Claire Deback, Laurent Arnaud, Alexis Mathian, Makoto Miyara, David Boutolleau, Christophe Parizot, Karim Dorgham, Laura Papagno, Victor Appay, Zahir Amoura, Guy Gorochov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22028659/pdf/?tool=EBI

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