miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients
<p>Investigation of therapy naïve human tumor and adjacent normal tissue biopsies demonstrated that expression levels of miRNAs are altered at and between stages of CRC. Targets of these altered miRNAs are members of the Insulin signaling pathways. Phosphorylation states of several mo...
Main Author: | David L. Knowlton, Kim Tang, Peter V. Henstock, Romesh R. Subramanian |
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Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2011-01-01
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Series: | Journal of Cancer |
Online Access: | http://www.jcancer.org/v02p0490.htm |
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