miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients

<p>Investigation of therapy na&#239;ve human tumor and adjacent normal tissue biopsies demonstrated that expression levels of miRNAs are altered at and between stages of CRC. Targets of these altered miRNAs are members of the Insulin signaling pathways. Phosphorylation states of several mo...

Full description

Bibliographic Details
Main Author: David L. Knowlton, Kim Tang, Peter V. Henstock, Romesh R. Subramanian
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v02p0490.htm